City were given a stern test on a wet and windy night at a noisy Kassam Stadium but two goals from Raheem Sterling eventually saw them through.
In Pep Guardiola's 100th match in charge of the Manchester club, captain De Bruyne led from the front as City outclassed the Gunners, who have now suffered six home games without a win. Images from the EPL matches played on Sunday.
Sancho, who has played 58 league games since joining United in 2021, said he respects all decisions made by the coaching staff.
Arsenal's winger Samir Nasri has hinted that he may leave the club this summer and join rivals Manchester United.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
Defender Raphael Varane scored his first Premier League goal as Manchester United returned to winning ways with a comfortable 3-0 victory over Brentford on a night of potential farewells at Old Trafford. Bruno Fernandes and Cristiano Ronaldo, the latter with a penalty, also netted on Monday, which is the last home fixture of a difficult campaign for United.
ManchesterCity and Manchester United scored 10 goals between them and boosted their title aspirations with convincing wins over NorwichCity and Fulham respectively on an eventful afternoon in the Premier League on Saturday.
Images from the English Premier League matches played on Sunday night.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
Manchester City roared back to the top of the Premier League with a 6-1 thrashing of Bournemouth after Manchester United steadied the ship
Match-by-match facts and statistics ahead of the first round of Premier League fixtures from August 5-7 (all times IST).
Manchester United's troubled season hit a new low on Saturday as Jose Mourinho saw his gamble on introducing a new tactical system backfire with an insipid 3-1 defeat to West Ham United in the Premier League.
Arsenal's third successive league win lifted them above West Ham United into fifth place with 45 points, one behind Manchester United but having played two fewer games.
IMAGES from the English Premier League matches played on Sunday.
England begin their World Cup group campaign against Iran on November 21.
The defeat halted Brighton's impressive three-game winning streak which included a 4-1 win over Chelsea and a 3-1 victory at Arsenal in the League Cup on Wednesday.
Manchester City needed Gareth Barry's stoppage-time winner to earn a 1-0 win at home to bottom club Reading on Saturday and exert some pressure on Premier League leaders Manchester United.
A ninth successive win in all competitions for United was celebrated with real vigour, as they moved to within a point of City in second, giving Arsenal the chance to go eight points clear at the top of the standings with a win over Tottenham Hotspur on Sunday.
In the Premier League, Arsenal is placed at the eighth position whereas United is positioned at the 11th place.
IMAGES from League Cup matches played on Wednesday.
Arsenal handed the Premier League initiative back to leaders Manchester United on Saturday with a limp performance in a goalless home draw against a Sunderland side who had lost their previous four games.
Arsenal ended their seven match winless run in the Premier League with a surprise 3-1 London derby victory over Chelsea at the Emirates Stadium on Saturday while Manchester United were held to a 2-2 draw at Leicester City.
German midfielder Mesut Ozil has joined Arsenal from Real Madrid in 40 million deal on Monday, it has been reported.
Arsenal took the race to the final day last season and are strongly tipped to end Manchester City's dominance this time.
Arsenal dominated the opening period in the Villa Park sunshine.
'It gives a strong answer to all the questions that were raised during the week'
Ronaldo's moments of brilliance, however, are getting ever rarer. Even in the Europa League, where he has started all four matches against mediocre opponents such as Sheriff Tiraspol and Omonia Nicosia, he has only scored once, off a penalty.
Mario Balotelli's stoppage-time penalty lifted Premier League leaders Manchester City to a dramatic 3-2 win over Tottenham Hotspur and Manchester United remained snapping at their heels with a 2-1 victory at Arsenal on Sunday.
Manchester United consolidated their fourth place, on 22 points, after first-half goals from Chris Smalling and Wayne Rooney and a brilliant, morale-boosting strike from Robin van Persie after the break sealed a 3-0 victory over Hull City.
Manchester City stayed ahead of age-old local rivals Manchester United at the top of the Premier League on Saturday with a deserved 1-0 win away to champions Chelsea.
IMAGES from Europa League matches played on Thursday.
Images from Sunday's action in the Premier League
Keeping pace with the changing times, star players of English Premier League giants Manchester United, Arsenal FC and Manchester City wished their vast Indian fan base on the occasion of Diwali.
Manchester City took a major step towards retaining their Premier League title with a 1-0 win over second-placed Chelsea on Saturday, opening up a 13-point lead at the top of the table for Pep Guardiola's side.
The top four failed to muster a goal on Saturday as Chelsea, Liverpool and Manchester United drew 0-0 while Arsenal went down 3-0 at Manchester City. Premier League leaders Chelsea could find no way through Newcastle United at Stamford Bridge. Liverpool had the same problem at home to Fulham and third-placed Manchester United were held 0-0 in a lively game at Aston Villa.
A summary of Saturday's action in the FA Cup third round.
Champions Chelsea and second-placed Manchester United beat Middlesbrough and Portsmouth respectively in the Premier League.
IMAGES from the Premier League matches played across England, on Sunday.
Chelsea manager Carlo Ancelotti has told arch rivals Arsenal that its time to show their mettle for the Premier League title.
Champions Manchester City slipped to a shock first Premier League defeat of the season at Wolverhampton Wanderers on Saturday, while Manchester United's campaign of woe continued with a loss to Crystal Palace.